The purpose is to determine if the lining of the uterus (endometrium) is maturing at the proper rate to permit a fertilized egg to implant and to grow. The test is performed here at The Beach Center.
When is it done and what are we looking for?
It is performed on the 12th luteal day or 2 days before an expected menses. During the luteal phase, the lining of the uterus undergoes specific cell changes. By microscopic examination of a small sample of the uterus lining, we can tell if your endometrium is changing properly.
What do we consider a "normal" or an "abnormal" biopsy?
Research has shown that the uterus lining undergoes specific cellular changes daily from the first day after ovulation to the next menses. The endometrial biopsy will let us know if your uterine lining is changing at the proper rate. If it is, your biopsy is "in-phase" or normal. If it is not, it is "out-of-phase" or abnormal.
What is the treatment for a biopsy that is "out of phase?"
The treatment depends on the cause of the out of phase lining. Finding the cause requires further evaluation of your cycle, called cycle monitoring, using ultrasound and blood hormone levels to follow follicle (egg) development. Depending on the outcome of cycle monitoring you may be treated by using poresterone, suppositories or injections, Clomid and/or Pergonal.
